Systemic Lupus Erythematosus

Autoimmune Multisystem Disorder

Understanding Systemic Lupus Erythematosus: Symptoms, Diagnosis & Advanced Care

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune inflammatory disorder that can affect multiple organ systems including the skin, joints, kidneys, brain, and other organs, causing pain, inflammation, and potential organ damage. Unlike localized autoimmune conditions, SLE occurs when the immune system mistakenly attacks healthy tissues throughout the body. Early diagnosis and targeted treatment are crucial to managing symptoms, preventing organ damage, and improving quality of life. At IRIS Centre for Rheumatology, we offer world-class, patient-centric care for SLE using the latest advances in rheumatology.

Systemic Lupus Erythematosus can affect anyone at any age, but it most commonly begins between the ages of 15 and 45. Women are affected much more frequently than men. The condition may cause systemic inflammation affecting the skin, joints, kidneys, brain, heart, lungs, and blood vessels. At IRIS, our multidisciplinary team ensures comprehensive management from early diagnosis to long-term remission strategies.

With our state-of-the-art immunodiagnostic laboratory, musculoskeletal ultrasound, and personalized treatment plans — including immunosuppressants, biologics, and antimalarials — we aim to halt disease progression, relieve symptoms, and restore quality of life. Healing begins with expert care and compassion.

Common Symptoms of Systemic Lupus Erythematosus

SLE symptoms can vary in severity and may come and go. Early recognition leads to better outcomes.

• Butterfly-shaped rash across cheeks and nose
• Joint pain, swelling, and stiffness
• Fatigue, fever, and weight loss
• Photosensitivity (rash after sun exposure)
• Kidney inflammation (lupus nephritis)
• Chest pain, hair loss, mouth ulcers